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Benzyl Alcohol

Commonly used in:

IMIQUIMOD, METROCREAM, METRONIDAZOLE, METROLOTION, Avar LS
Associated with immunotoxicity or allergies. Classified as toxic or harmful

SKNV prescription skincare is safe for all skin types and free from harmful additives and common allergens.

Corazza M, Mantovani L, Maranini C, Virgili A. Allergic contact dermatitis from benzyl alcohol. Contact Dermatitis. 1996 Jan;34(1):74-5. doi: 10.1111/j.1600-0536.1996.tb02129.x. PMID: 8789242.

https://pubmed.ncbi.nlm.nih.gov/8789242/

 

Curry EJ, Warshaw EM. Benzyl alcohol allergy: importance of patch testing with personal products. Dermatitis. 2005 Dec;16(4):203-8. PMID: 16536335.

https://pubmed.ncbi.nlm.nih.gov/16536335/

 

Guin JD, Goodman J. Contact urticaria from benzyl alcohol presenting as intolerance to saline soaks. Contact Dermatitis. 2001 Sep;45(3):182-3. doi: 10.1034/j.1600-0536.2001.045003182.x. PMID: 11553157.

https://pubmed.ncbi.nlm.nih.gov/11553157/

 

Kubin ME, Riekki R. Benzyl alcohol allergy mimicking corticosteroid allergy. Contact Dermatitis. 2016 Jul;75(1):58-9. doi: 10.1111/cod.12562. PMID: 27264293.

https://pubmed.ncbi.nlm.nih.gov/27264293/

 

Lazzarini S. Contact allergy to benzyl alcohol and isopropyl palmitate, ingredients of topical corticosteroid. Contact Dermatitis. 1982 Sep;8(5):349-50. doi: 10.1111/j.1600-0536.1982.tb04253.x. PMID: 6216057.

https://pubmed.ncbi.nlm.nih.gov/6216057/

 

Li M, Gow E. Benzyl alcohol allergy. Australas J Dermatol. 1995 Nov;36(4):219-20. doi: 10.1111/j.1440-0960.1995.tb00980.x. PMID: 8593115.

https://pubmed.ncbi.nlm.nih.gov/8593115/

 

Podda M, Zollner T, Grundmann-Kollmann M, Kaufmann R, Boehncke WH. Allergic contact dermatitis from benzyl alcohol during topical antimycotic treatment. Contact Dermatitis. 1999 Nov;41(5):302-3. doi: 10.1111/j.1600-0536.1999.tb06175.x. PMID: 10554077.

https://pubmed.ncbi.nlm.nih.gov/10554077/

 

Sestini S, Mori M, Francalanci S. Allergic contact dermatitis from benzyl alcohol in multiple medicaments. Contact Dermatitis. 2004 May;50(5):316-7. doi: 10.1111/j.0105-1873.2004.00341c.x. PMID: 15209815.

https://pubmed.ncbi.nlm.nih.gov/15209815/

 

Simm R, Kvalvaag AS, van Deurs B, Lindbäck T, Sandvig K. Benzyl alcohol induces a reversible fragmentation of the Golgi apparatus and inhibits membrane trafficking between endosomes and the trans-Golgi network. Exp Cell Res. 2017 Aug 1;357(1):67-78. doi: 10.1016/j.yexcr.2017.04.025. Epub 2017 Apr 25. PMID: 28450044.

https://pubmed.ncbi.nlm.nih.gov/28450044/

 

Tripp M, Ribeiro M, Kmiecik S, Go R. A “”Rash”” Decision in Anesthetic Management: Benzyl Alcohol Allergy in the Perioperative Period. Case Rep Anesthesiol. 2021 Jun 24;2021:8859823. doi: 10.1155/2021/8859823. PMID: 34258071; PMCID: PMC8249123.

https://pubmed.ncbi.nlm.nih.gov/34258071/

 

Verecken P, Birringer C, Knitelius AC, Herbaut D, Germaux MA. Sensitization to benzyl alcohol: a possible cause of “”corticosteroid allergy””. Contact Dermatitis. 1998 Feb;38(2):106. doi: 10.1111/j.1600-0536.1998.tb05662.x. PMID: 95

https://pubmed.ncbi.nlm.nih.gov/9506225/06225.

 

Würbach G, Schubert H, Phillipp I. Contact allergy to benzyl alcohol and benzyl paraben. Contact Dermatitis. 1993 Mar;28(3):187-8. doi: 10.1111/j.1600-0536.1993.tb03387.x. PMID: 8462301.

https://pubmed.ncbi.nlm.nih.gov/8462301/